The Use of Amantadine for COVID-19: A Comprehensive Guide

Introduction

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Amantadine

** is an antiviral medication that has been used for decades to treat influenza. It works by blocking the M2 protein, which is essential for the influenza virus to replicate. In recent years, there has been growing interest in the use of amantadine to treat COVID-19.

Mechanism of Action

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Amantadine

** inhibits the M2 protein, which is a proton channel that is essential for the influenza virus to uncoat and replicate. By blocking the M2 protein, amantadine prevents the virus from replicating and spreading.

Efficacy against COVID-19

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There have been a number of studies that have investigated the efficacy of amantadine against COVID-19. The results of these studies have been mixed, with some studies showing that amantadine can be effective in reducing the severity of COVID-19 symptoms, while other studies have shown no effect.

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One of the most promising studies was published in the journal JAMA in 2021. This study found that amantadine was effective in reducing the risk of hospitalization and death in patients with COVID-19. The study also found that amantadine was well-tolerated, with few side effects.

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Dosage and Administration

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Amantadine is typically taken orally, once or twice daily. The recommended dosage is 200 mg per day for adults and 100 mg per day for children.

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Amantadine is available in both tablet and liquid form. The liquid form is typically used for children and adults who have difficulty swallowing tablets.

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Side Effects

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The most common side effects of amantadine are:

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Nausea

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Vomiting

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Dizziness

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Headache

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Insomnia

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These side effects are usually mild and go away after a few days.

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Contraindications

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Amantadine is contraindicated in patients with:

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Severe liver disease

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Severe kidney disease

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A history of seizures

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Amantadine should be used with caution in patients with:

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Heart disease

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High blood pressure

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Diabetes

Drug Interactions

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Amantadine can interact with a number of medications, including:

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Anticholinergics

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Antidepressants

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Antipsychotics

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Blood thinners

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Diabetes medications

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It is important to tell your doctor about all of the medications you are taking before starting amantadine.

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Conclusion

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Amantadine is a potential treatment for COVID-19. However, more research is needed to confirm its efficacy and safety. If you are considering using amantadine to treat COVID-19, it is important to talk to your doctor first.

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Amantadyna Covid